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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKTIP All Species: 27.27
Human Site: S279 Identified Species: 46.15
UniProt: Q9H8T0 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H8T0 NP_001012398.1 292 33128 S279 L S W V K P G S V Q P F S K E
Chimpanzee Pan troglodytes XP_001166382 293 33238 G279 G L S W V K P G S V Q P F S K
Rhesus Macaque Macaca mulatta XP_001085712 292 33132 S279 L S W V K P G S V Q P F S K E
Dog Lupus familis XP_863328 286 32246 S273 L S W V K P G S V Q P F S K E
Cat Felis silvestris
Mouse Mus musculus Q64362 292 32923 S279 L S W V K P G S V Q P F S K E
Rat Rattus norvegicus Q5FVH4 292 32973 S279 L S W V K P G S V Q P F S K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520209 412 45602 K396 V S G L S W V K P G S V Q P F
Chicken Gallus gallus Q5ZJJ5 293 33286 G279 G L S W V K P G S V Q P F S K
Frog Xenopus laevis Q498F8 293 33438 S280 L S W V K P G S V L P F S K E
Zebra Danio Brachydanio rerio Q7ZYX1 293 33182 S280 L S W V K P G S T Q P F S K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4V4 244 28114 W232 G H A T G L S W V K E G E F K
Honey Bee Apis mellifera XP_625209 266 31023 P254 L G L S W V Q P G S L Q P F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784185 277 31591 S264 N A Q T S G L S W I K P G N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P52490 153 17450 R141 Q G A K A K A R E W T K L Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 95.2 N.A. 96.2 95.8 N.A. 59.9 87.3 82.9 78.1 N.A. 32.8 35.6 N.A. 53.4
Protein Similarity: 100 99.6 99.6 95.8 N.A. 97.9 98.6 N.A. 63.8 94.8 91.1 88 N.A. 46.9 59.2 N.A. 68.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 6.6 0 93.3 93.3 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 20 6.6 93.3 93.3 N.A. 20 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 0 8 0 8 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 8 0 8 0 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 50 15 15 8 % F
% Gly: 22 15 8 0 8 8 50 15 8 8 0 8 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 0 0 8 50 22 0 8 0 8 8 8 0 50 22 % K
% Leu: 58 15 8 8 0 8 8 0 0 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 50 15 8 8 0 50 22 8 8 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 43 15 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 58 15 8 15 0 8 58 15 8 8 0 50 15 8 % S
% Thr: 0 0 0 15 0 0 0 0 8 0 8 0 0 0 0 % T
% Val: 8 0 0 50 15 8 8 0 50 15 0 8 0 0 0 % V
% Trp: 0 0 50 15 8 8 0 8 8 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _